In the lesson, the speaker discusses the PSCD (Personal, Social, and Career Development) topic, focusing on guidelines to protect each other during the COVID-19 pandemic, including social distancing to prevent virus transmission. The speaker explains the structure of the coronavirus, mentioning its appearance under a microscope, which resembles a crown due to its spike proteins, hence the name “coronavirus.” Additionally, scientific tools like microscopes are highlighted for their role in observing microorganisms and conducting experiments.